Immunological inefficiency of art in HIV-infected patients
نویسندگان
چکیده
Widespread introduction and early initiation of antiretroviral therapy significantly improves the prognosis in people living with HIV — an increase number CD4+ T-lymphocytes, incidence HIV-related diseases mortality rate decreases. Despite suppression replication, a fraction ART-treated patients fails to achieve normalization T-cell counts. These have increased risk clinical progression AIDS non-AIDS events. Currently, there are no clear criteria for determining case immunological inefficiency ART. To date, mechanisms incomplete immune reconstitution HIV-infected not been fully elucidated. Therefore, this review, we aim attract attention specialists problem summarized results recent studies current literature data, described possible factors development ART; presented studied therapeutic strategies aimed at recovering immunity patients.
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ژورنال
عنوان ژورنال: ???-???????? ? ???????????????
سال: 2023
ISSN: ['2077-9828', '2078-1792']
DOI: https://doi.org/10.22328/2077-9828-2023-15-2-7-18